Dr. Sampa Saha
  • About
  • Education and Training
  • Awards & Grants
  • Professional and Research Experience
  • Research
  • Publications
  • Teaching
  • Students
  • Contact
  • About
    A polymer scientist, teacher and consultant, Sampa Saha is the Assistant Professor of CPSE at IIT, Delhi. Her research area spans from biodegradable polymeric particles (multi-layered and multi-compartmental) to polymer brushes. She emphasizes on multi-disciplinary approach to solve problems and hence believes in strong collaborative efforts.
  • Education and Training
    • Ph.D., Polymer Chemistry, Michigan State University (MSU), USA, 2004-2009.
    • M.Tech., Rubber Technology, I.I.T., Kharagpur, India, 2001-2003.
    • B.Tech., Polymer Science and Technology, Calcutta University, India, 1998-2001.
  • Awards & Grants
    • Awarded with €800,000 as research funding for 2 years from BASF, Germany, 2011
    • Secured second rank in IIT Kharagpur during M.Tech., 2003
    • 3rd rank, All India Quiz competition on Polymer Science and Technology, 2002
    • College topper, B.Sc. (Chemistry), 1998
  • Professional and Research Experience

    2015-Present

    Assistant Professor, Centre for Polymer Science and Engineering, IIT, Delhi.

    2014-2015

    Research Fellow, School of Materials Science and Engineering, Nanyang Technological University, Singapore; led a team of 5. Advisor: Professor Joachim Loo

    • Developed a multi-layered polymeric particle system for therapeutic applications.

    2013-2014

    Senior Research Chemist, Prochem Solutions Pvt. Ltd., Singapore
    • Worked with a multi-disciplinary team on micro/nano encapsulation projects

    • Developed a personal care product for cosmetic applications – synthesis of micro particles with non-leachable core using emulsion polymerization

    Measurable fact: Enhanced properties by microencapsulation compared to the existing product. Performed best among the similar candidates of its genre.

    • Worked with business team to identify the market needs of microencapsulation

    • Filed novel ideas as invention disclosure within the company

    2011-2012

    Research Scientist, BASF South East Asia Pvt. Ltd., Singapore
    • led projects with a group of 4

    • Developed an anti-infective central venous catheter coating - performance under review

    Measurable fact: Increased anti-infective properties; self-designed reaction scheme for the coating stood out best among the other schemes Received €800,000 as funding for 2 years from a self-written grant proposal on ‘Tunable degradation of biodegradable functional polymer’ Role: Principal Invigilator.

    2009-2011

    Postdoctoral Research Associate, Chemical Engineering, University of Michigan, Ann Arbor, MI, USA,

    Advisor: Professor Joerg Lahann
    • Developed a novel strategy to synthesize shape shifted biodegradable microcylinders via spatio-selective growth of polymer brush using ATRP.

    • Demonstrated bio-conjugation on chemically orthogonal three-patch microparticles.

    2004-2009

    Ph.D. student, Michigan State University, East Lansing, MI, USA; Advisor: Late Professor Gregory L. Baker

    • Surface initiated polymerization of azido propyl methacrylates and its elaboration via click chemistry

    Measurable fact: A novel approach for the covalent modification of solid surface with water-soluble polymers and tuning its hydrophilicity.

    • Studied the substituent effect of polystyrene brushes using surface-initiated Atom Transfer Radical Polymerization (ATRP) from Au and Si substrates Measurable fact: Unprecedented high growth rates were observed for styrene monomers substituted with electron withdrawing groups.

    • Found some unique and distinctive surface phenomena on gold substrate during surface initiated ATRP, which was absent in other substrates like silicon. Measurable fact: Revealed the problem of growing thick brush on gold surface and solved it by forming a cross-linked poly (siloxane) primer layer on the gold surfaces

    2003-2004

    Lecturer, Amrita University, Coimbatur, TamilNadu.

    2003-2003

    Project Assistant, Rubber Technology Centre, Indian Institute of Technology, Kharagpur, India.

    Advisor: Professor Anil K. Bhowmick

    • Developed a novel water based eco-friendly adhesive from a plant-based gum

    2002-2003

    M.Tech. Project Research Assistant, National Chemical Laboratory, Pune, India.

    Advisors: Dr. Prakash P. Wadgaonkar and Professor G.B. Nando.

    • Synthesis of aromatic polyamide from cashew nut shell oil.

  • Research
    Research Areas: Our research interests mostly include emerging technologies to fabricate multi-compartmental/multi-layered polymeric particles and surface modification with polymer brushes. Some of our recent works have been stated below.
    1. Multi-compartmental polymeric particles – Electrohydrodynamic co-jetting
    In recent years, particle technologies have been broadly focused on manipulation of size and shape. The electro hydrodynamic co-jetting of different polymer solutions leads to a unique design of particles with multiple and distinct surface patterns or nano-compartments. Moreover, the ability to selectively modify individual areas on the surface of a particle, cylinder or a fiber is another important physico-chemical property, which necessitates anisotropic distribution of interfacial binding sides. We have demonstrated different types of spatio-selective surface modification of individual compartments to generate patchy surfaces, which may form shape shifted microcylinders. We have also shown selective degradation of one compartment in presence of others.
    2. Multilayered particles
    Particulate systems, regardless micron or nano-sized, play an important role in various applications. In recent years, multi-layered including core-shell, particles have been developed and exploited for a number of applications ranging from biomedical, catalysis, diagnostic, and energy to wastewater treatment. While some multi-layered particles are designed to be wholly inorganic-based, a substantial proportion of these functionalized particles are designed using polymers. Polymers may play a role as a template, a material component of the particle or may be employed in the full design of the particle. The key applications of multi-layered particles has been highlighted, while addressing to the role of polymers in the architectural design of these functionalized, application-driven particles.

    J. Mater. Chem. B, 2015, 3, 3406-3419. Polymer, 2015, in press.

    3. Polymer brush synthesis
    Synthesis of well-defined functional nanobrushes is highly desirable. Controlling the functionality of the functional brush is even more attractive. In this particular example, azido propyl methacrylate (AZPMA) have been synthesized and successfully grown from gold surface via surface initiated ATRP and also copolymerized it in random fashion with hydrophilic monomer like oligo ethylene glycol methacrylate (PEGMA) to control the functionality as well as hydrophilicity of the mixed random brush. Subsequent post-functionalization of homo and copolymer brushes was demonstrated by appending an alkyne-modified dye to AZPMA via click reactions which was very fast (> 60% conversion in 1 min). In the case of water soluble high molecular weight alkynes, surface-grafted copolymers with highest amount of hydrophilic monomer (PEGMA) gave the highest degree of immobilization, which indicates its potential application in bioconjugation.

    J. Appl. Polym. Sci. 2015, 132, 41363.
    Macromolecules 2012, 45(22), 9063-9069.
    ACS Applied Materials and Interfaces 2011, 3(8), 3042-3048.
    Langmuir 2007, 23(23), 11360-11365.

  • Publications
    1. Conducting polymer tethered on surface via grafting from approach.
    Saha, Sampa; Baker, Gregory L. J. Appl. Polym. Sci. 2015, 132, 41363 [Impact factor:1.64]

    2. Chemically orthogonal three-patch microparticles. (inside cover article)
    S. Rahmani, S. Saha, H. Durmaz, A. Donini, A. C. Misra, J. Yoon, J. Lahann, Angewandte Chemie International Edition, 2014, 126(9), 2364 (selected as a Hot paper and ‘Press Release’ article; Highlighted in Phys.Org: ‘http://phys.org/news/2014-02-3d-microparticles-chemically-independent-patches.html’) [Impact factor:13.5]

    3. Chemically Controlled Bending of Compositionally Anisotropic Microcylinders.
    S. Saha, D. Copic, S. Bhaskar, N. Clay, A. Donini, A. J. Hart, J. Lahann, Angewandte Chemie International Edition 2012, 51(3), 660-665, S-660/1-S-660/8. [Impact factor:13.5]

    4. Surface-Initiated Polymerization of Azidopropyl Methacrylate and Its Film Elaboration via Click Chemistry.
    Saha, Sampa; Bruening, Merlin L.; Baker, Gregory L. Macromolecules 2012, 45(22), 9063-9069. [Impact factor: 5.8]

    5. Facile synthesis of thick films of Poly (methyl methacrylate), Poly (styrene) and Poly (vinyl pyridine) from Au surfaces.
    Saha, Sampa; Bruening, Merlin L.; Baker, Gregory L. ACS Applied Materials and Interfaces 2011, 3(8), 3042-3048. [Impact factor: 6.7]

    6. Completely Aqueous Procedure for the Growth of Polymer Brushes on Polymeric Substrates.
    Jain, Parul; Dai, Jinhua; Grajales, Sebastian; Saha, Sampa; Baker, Gregory L.; Bruening, Merlin L. Langmuir 2007, 23(23), 11360-11365. [Impact factor: 4.5]

    7. Substituent effects in ATRP of polystyrene brushes.
    Saha, Sampa; Bruening, Merlin L.; Baker, Gregory L.

    Polymer Preprints (American Chemical Society, Division of Polymer Chemistry) 2007, 48(1), 783. (submitted to European Polymer Journal)

    8. Studies of Terminalia bellerica (Bahera), a natural gum, as an additive in a water-based adhesive composition.
    Saha, Sampa; Singha, Nikhil K.; Chattopadhyay, R. N.; Ganguly, Anirban; Bhowmick, Anil K. J. Adh. Sci. Tech. 2005, 19(15), 1349-1361. [Impact factor: 0.96]
    Reviews

    9. Recent Developments in Multilayered Polymeric Particles – From Fabrication Techniques to Therapeutic Formulations

    Sampa Saha, Say Chye Joachim Loo J. Mater. Chem. B, 2015, 3, 3406-3419. [Impact factor: 6.6]

    10. Application-driven multi-layered particles - The role of polymers in the architectural design of particles (cover article)
    Sampa Saha, Say Chye Joachim Loo Polymer, 2015, in press. [Impact factor: 3.9]

    Book Chapter

    11. Properties and Applications of Polymer Nanocomposites: Chapter 3, Handbook of Manufacturing Engineering and Technology, 2014, Springer publisher.

    Alok Chaurasia, Yu Suzhu, Cheng Kuo Feng Henry, Vishal Tukaram Mogal, Sampa Saha.

    Patent

    12. An adhesive composition and a process for the preparation thereof.

    Sampa Saha, Nikhil K. Singha, Anil K. Bhowmick, R. N. Chattopadhyay Indian Patent. 00539/KOL/2003A.
    Conference Presentations

    1. Saha, Sampa; Bruening, Merlin L.; Baker, Gregory L. Polymerization of azidopropyl methacrylates from surfaces and their elaboration via click chemistry. Abstracts of Papers, 243rd ACS National Meeting & Exposition, San Diego, CA, United States, March 25-29, 2012 (2012), PMSE-248.

    2. Saha, Sampa; Bhaskar, Srijanani; Clay, Nichoclas; Lahann, Joerg. Controlled bending in bicompartmental microcylinders. Abstracts of Papers, 241st ACS National Meeting & Exposition, Anaheim, CA, United States, March 27-31, 2011 (2011), POLY-282.

    3. Saha, Sampa; Baker, Gregory L. Conducting polymer tethered on surface via grafting from approach. Abstracts of Papers, 237th ACS National Meeting, Salt Lake City, UT, United States, March 22-26, 2009 (2009), POLY-253.

    4. Saha, Sampa; Bruening, Merlin L.; Baker, Gregory L. Effect of substrate in surface ATRP. Abstracts of Papers, 236th ACS National Meeting, Philadelphia, PA, United States, August 17-21, 2008 (2008), POLY-409.

    5. Saha, Sampa; Bao, Zhiyi; Bruening, Merlin L.; Baker, Gregory L. Substituent effects in ATRP of polystyrene brushes. Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29 2007 (2007), POLY-465.
  • Teaching
    • Biodegradable Polymeric Materials(PTL714)
    • Polymer Chemistry Lab(PTP709)
    • Professional Social Ethics & Responsibility (NEN100)
  • Students


    AGNI KUMAR BISWAL
    Email: agni.biswal@gmail.com
    ptz148397@polymers.iitd.ac.in

    Development of Controlled release of packaging films using multilayered polymeric microparticles



    IFRA
    Email: iframirza333@gmail.com

    Development of multicompartmental ‘smart’ polymeric particles



    MOHD SHAHNUR USMANI
    Email: Shahnuruengg786@gmail.com

    Antimicrobially active biodegradable packaging film



    T.GANGAIARASI
    Email: gangaiarasi@gmail.com

    Studies on PLA/EVA with Hallosite



    M.SNEHA SREE
    Email: snehasreemullapudi@gmail.com

    Studies the effect of Wood flour on the Properties of PLA/EVA Biodegradable composites

  • Contact
    Office Contacts :
    Address : TX-102, Centre for Polymer Science & Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi - 110016
    Tel. : +911126596692
    Fax : +911126591421
    Email : ssaha@polymers.iitd.ac.in
    Residence Contacts :
    Address :17, IP Apartments, Indian Institute of Technology Delhi, Hauz Khas, New Delhi - 110016
    Tel. : +911126591573
    Email : ssaha@polymers.iitd.ac.in